Usefulness of Omalizumab and Sting Challenge Test in Hymenoptera Venom Allergy and Mastocytosis

The sting challenge test in Hymenoptera venom allergy. Position paper of the Subcommittee on Insect Venom Allergy of the European Academy of Allergology and Clinical Immunology.

Hymenoptera venom allergy: taking the sting out of difficult cases.

BACKGROUND Correct identification of the culprit venom is a prerequisite for specific venom immunotherapy. OBJECTIVE To assess whether the basophil activation test (BAT) constitutes an additional diagnostic instrument in patients with equivocal or negative specific immunoglobulin (Ig) E or venom skin test (VST) results. METHODS One hundred eighteen patients with a compelling history of IgE-...

Mastocytosis and insect venom allergy.

PURPOSE OF REVIEW To analyse the association of systemic allergic hymenoptera sting reactions with mastocytosis and elevated baseline serum tryptase and to discuss diagnosis and treatment in patients with both diseases. RECENT FINDINGS In recent large studies on patients with mastocytosis a much higher incidence of severe anaphylaxis following hymenoptera stings than in the normal population ...

Tryptase and Hymenoptera Venom Allergy

Antecedentes: La gravedad de la reacción tras una picadura de himenópteros se ha relacionado con la presencia de niveles elevados de triptasa sérica. El propósito del estudio fue cuantifi car los niveles basales de triptasa en pacientes con alergia al veneno de himenópteros e investigar la posible correlación entre estos niveles y la gravedad de la reacción a la picadura. Métodos: Participaron ...

Diagnosis of Hymenoptera venom allergy.

The purpose of diagnostic procedure is to classify a sting reaction by history, identify the underlying pathogenetic mechanism, and identify the offending insect. Diagnosis of Hymenoptera venom allergy thus forms the basis for the treatment. In the central and northern Europe vespid (mainly Vespula spp.) and honeybee stings are the most prevalent, whereas in the Mediterranean area stings from P...